Gastroenterology and Anorectal Compounding

Rectal & Anal Tissue Support

Personalized topical and mucosal preparations designed to provide localized delivery of medications for rectal and anal comfort.

Reviewed by Linda Pungpravat, Compounding Pharmacist, RPh Mixwell Compounding Pharmacy, Chino, CA

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Rectal & Anal Tissue Support

Signs people notice

  • Requirement for custom medication strength
  • Sensitivity
  • Preference for localized rather than systemic therapy

Clinical Overview

This service provides healthcare providers with options for customized medication strengths and combinations that are not available in standard over-the-counter or commercial rectal preparations.

  • Formulation Logic: Pharmacists can combine diverse classes of pharmaceutical actives—such as vasodilators (e.g., Nifedipine or Diltiazem), localized anesthetics (Lidocaine), and corticosteroids (Hydrocortisone)—into a single, uniform vehicle.
  • Targeted Delivery: Formulations are designed to act locally on the affected tissue, which may reduce the potential for systemic side effects often associated with oral medications.
  • Base Technology: Preparations are often compounded in specialized bases like VersaPro™ Anhydrous or specialized muco-adhesive gels that are engineered to remain in contact with the mucosal lining for an extended period.

Common Formulas Prescribers Order for This

Non-sterile compounded mucoadhesive r...Lidocaine / Nifedipine Rectal Gel (MucoLmox™ / VersaBase®)Technical details Cream · TopicalDiltiazem Topical Cream (VersaBase®)A compounded diltiazem cream, commonly 2%, prepared in Chino, CA to a prescriber's order for perianal application in ...Technical details Anhydrous topical gel Amlodipine Topical GelTechnical details Anhydrous topical/rectal prepLidocaine - Amlodipine - Diazepam TopicalTechnical details

Each formula is prepared only with a valid prescription. Your prescriber decides what is appropriate.

Compounded in Chino, CA. Delivered across California.

  • Chino
  • Chino Hills
  • Ontario
  • Pomona
  • Diamond Bar
  • Rancho Cucamonga
  • Eastvale
Mixwell Compounding Pharmacy 13788 Roswell Ave, Ste 158, Chino, CA 91710
(909) 378-7301

Mixwell is a state licensed, non sterile compounding pharmacy and a PCCA member, preparing each formula in a lab built to USP 795 and USP 800 standards. Compounded medications are not reviewed or approved by the FDA and are dispensed only with a valid prescription. We do not prepare sterile products or injectables. Nothing here promises a specific result, and compounded preparations are not presented as superior to commercially available products. Mixwell does not accept insurance. Call for pricing.

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