Hydroquinone 6%/Kojic Acid 6%/Hydrocortisone 0.5%/Tretinoin 0.025% Topical Gel

WO6 Anhydrous (Water-Free)

Mechanism of Action

Commonly Requested Formulas for Patients Requesting Skin Bleaching/Skin Lightening:
WO6 Anhydrous is an elegant, stable base that is suitable for
a broad range of dermatological or cosmetic applications

This preparation is a practitioner-directed formulation combining four specific active agents: Hydroquinone, Kojic Acid, Hydrocortisone, and Tretinoin.

  • Synergistic Delivery: The solution is designed as a "multi-modal" approach by utilizing a retinoid (Tretinoin) and the depigmenting agents (Hydroquinone and Kojic Acid).
  • Irritation Management: The inclusion of a mild corticosteroid (Hydrocortisone) is intended to manage potential localized irritation often associated with concentrated retinoid or hydroquinone use [1].
  • Anhydrous Advantage: This formulation is compounded in WO6® Anhydrous Topical Gel, a specialized base that contains no water. Many active ingredients, particularly Hydroquinone and Vitamin C derivatives, are chemically unstable in aqueous (water-based) environments and can oxidize rapidly. The WO6 base protects these ingredients from degradation, ensuring the formulation maintains its pharmaceutical potency throughout the duration of use [3].

Medical Disclaimer: This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a skin condition.

Compounding Disclaimer: Compounded medications are not FDA-approved. This means that the FDA does not verify the safety or effectiveness of compounded drugs. Compounded preparations are customized by a licensed pharmacist upon receipt of a valid patient-specific prescription from a licensed practitioner. Mixwell Pharmacy makes no claims regarding the clinical efficacy or superiority of these preparations over FDA-approved manufactured products.

Clinical Advantages

  • ✓ Patient-Preferred Texture: Unlike traditional heavy creams, the WO6 gel is non-greasy, non-tacky, and leaves a silky finish, which supports patient adherence to the prescribed regimen [3].
  • ✓ Preservative-Free Customization: Because the base is anhydrous, it does not require the traditional preservatives or parabens often found in commercial skin creams, making it a suitable option for patients with high chemical sensitivities.
  • ✓ Targeted Concentration: Compounding allows a healthcare provider to specify exact percentages (e.g., 6% Hydroquinone vs the standard 4%) that are not available in mass-produced formats

Want to learn more about Hydroquinone 6%/Kojic Acid 6%/Hydrocortisone 0.5%/Tretinoin 0.025% Topical Gel

Are you a healthcare provider or patient in Chino, Chino Hills, Ontario, Eastvale, Rancho Cucamonga, or Upland? Mixwell Pharmacy provides specialized pharmaceutical support throughout San Bernardino, Los Angeles, and Orange Counties. Contact our Chino laboratory to learn how we facilitate customized Hydroquinone 6%/Kojic Acid 6%/Hydrocortisone 0.5%/Tretinoin 0.025% Topical Gelfor practitioners across Southern California.

(909) 378-7301

Serving Los Angeles County, Orange County, San Bernardino County, Riverside County, Ventura County, and the Inland Empire