The troche is a small, lozenge-like dosage form designed to dissolve slowly between the cheek and gum (buccal) or under the tongue (sublingual).
- This delivery method allows the active pharmaceutical ingredients—typically Estradiol, Estriol, and/or Progesterone—to be absorbed directly through the highly vascularized oral mucosa.
- By entering the bloodstream via the mucosal lining, the medication avoids "first-pass metabolism" in the liver, which occurs with standard oral capsules.
- The base is often formulated with natural sweeteners and flavors to ensure patient compliance without the use of unnecessary commercial fillers.