Hormone & Cycle Balance

Clinical Overview

This service is designed for individuals requiring personalized hormone concentrations or specific dosage forms that are not available in mass-produced commercial products.

Formulation Logic: Pharmacists work with providers to create preparations using plant-sourced pharmaceutical ingredients such as Estradiol (E2), Estriol (E3), and Progesterone.
Customization: Formulations can be adjusted to be hypoallergenic—free of specific dyes, gluten, or preservatives—to accommodate individual patient sensitivities.

Commonly used Compounding Solutions

Testosterone Topical BHRT Cream (Lipoderm®)

Utilizes a transdermal delivery system designed to facilitate the absorption of pharmaceutical-grade active ingredients through the skin barrier.

The Lipoderm® technology is engineered to stabilize high concentrations of multiple active ingredients, such as Testosterone, Estradiol, Estriol, and Progesterone, in a single application.
By bypassing the digestive system (first-pass metabolism), this topical approach allows for the administration of customized concentrations as specifically determined by the prescribing practitioner to meet individual patient needs.

Technical Specifications →

BHRT Oral Capsule

Utilizes micronized hormones (such as Progesterone, Estradiol, or Estriol) to increase the surface area of the active pharmaceutical ingredients, which may support consistent absorption.

The hormones are encapsulated in a customized strength as specified by the practitioner to meet the unique physiological requirements of the patient.
Available in specialized filler bases that are free of common allergens like gluten, lactose, or synthetic dyes, ensuring compatibility for sensitive patients.

Technical Specifications →

Bi-Est / Progesterone Specialized Suppository

Designed for localized mucosal absorption, this delivery system utilizes a fatty acid base that melts at body temperature to release the active pharmaceutical ingredients.

The Ellage® Anhydrous component is engineered to be mucoadhesive, maintaining contact with the mucosal lining for a sustained period.
This formulation allows for the precise combination of Estradiol (E2), Estriol (E3), and Progesterone in ratios specifically requested by the prescribing clinician to meet the patient's unique physiological requirements.

Technical Specifications →

Sublingual BHRT Troche

The troche is a small, lozenge-like dosage form designed to dissolve slowly between the cheek and gum (buccal) or under the tongue (sublingual).

This delivery method allows the active pharmaceutical ingredients—typically Estradiol, Estriol, and/or Progesterone—to be absorbed directly through the highly vascularized oral mucosa.
By entering the bloodstream via the mucosal lining, the medication avoids "first-pass metabolism" in the liver, which occurs with standard oral capsules.
The base is often formulated with natural sweeteners and flavors to ensure patient compliance without the use of unnecessary commercial fillers.

Technical Specifications →

BHRT Vaginal Cream (Custom Estrogen/Progesterone)

This preparation utilizes MucoLox™ or Ellage® Anhydrous technology, which are specialized pharmaceutical bases designed to adhere to mucosal membranes for an extended duration.

The delivery system allows for the customized inclusion of bioidentical hormones—such as Estradiol (E2), Estriol (E3), and Progesterone—in precise concentrations determined by the prescribing practitioner.
By utilizing an anhydrous (water-free) base, the stability of the active hormone ingredients is maintained, and the need for harsh chemical preservatives is often reduced or eliminated.
The base is formulated with a tissue-friendly pH to minimize localized irritation in sensitive areas.

Technical Specifications →

Testosterone Topical BHRT Cream (Atrevis®)

Atrevis Hydrogel is an advanced topical base that uses a unique, hydrogel polymer network, along with natural enhancers to drive testosterone far beyond the reach of other bases.

By bypassing the digestive system (first-pass metabolism), this topical approach allows for the administration of customized concentrations as specifically determined by the prescribing practitioner to meet individual patient needs.

Technical Specifications →

Testosterone Topical BHRT Cream (Versabase®)

VersaBase Cream is an elegant, yet durable, topical cream andan ideal compounding base for topical and vaginal hormone replacement therapy(HRT). It simulates the natural moisturizing barrier of the skin through its emulsion system and rubs in quickly, leaving a soft and silky feel.

The Versabase® technology is engineered to stabilize high concentrations of multiple active ingredients, such as Testosterone, Estradiol, Estriol, and Progesterone, in a single application.
By bypassing the digestive system (first-pass metabolism), this topical approach allows for the administration of customized concentrations as specifically determined by the prescribing practitioner to meet individual patient needs.

Technical Specifications →

Related Symptoms

• Requirement for a unique hormone combination or strength.

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Hormone & Cycle Balance

Clinical Overview

Mixwell Compounding Pharmacy