This preparation is a practitioner-directed formulation designed for localized application to the rectal mucosa.
- It utilizes Diltiazem (1% – 2%), a calcium channel blocker, which is prepared in an anhydrous petrolatum base to ensure stability and a smooth, consistent texture for ease of application.
- The formulation may be compounded with Lidocaine (5%), a localized anesthetic, to provide a multi-modal approach within a single application.
- By applying the medication topically to the affected area, the active ingredients work locally on the tissue, providing a targeted alternative to systemic oral medications that may have broader metabolic effects.