For dermatologists managing androgenetic alopecia, a single topical solution combining minoxidil and finasteride offers a way to apply two mechanisms in one daily step. Mixwell Compounding Pharmacy in Chino, CA prepares TrichoSol™ — a Minoxidil 7.5% / Finasteride 0.1% topical solution — compounded to your prescription and supported by a beyond-use-date stability study.
Minoxidil 7.5% / Finasteride 0.1%
🧬 Two Mechanisms, One Daily Application
Androgenetic alopecia involves both follicular miniaturization and androgen-related pathways. Minoxidil and finasteride act through different mechanisms, which is why prescribers sometimes combine them.
💧 Minoxidil
A vasodilator long used topically for pattern hair loss. Topical minoxidil at 2% and 5% is FDA-approved and available over the counter; higher compounded strengths are prepared pursuant to a prescription.
🔬 Finasteride
A 5-alpha-reductase inhibitor that reduces conversion of testosterone to DHT. Oral finasteride is FDA-approved for male pattern hair loss; the topical route is a compounded, non-FDA-approved alternative some prescribers select to focus delivery at the scalp.
❓ Why combine minoxidil and finasteride in one topical solution?
The two act through separate mechanisms — minoxidil on the follicle and finasteride on the androgen pathway. Combining them in a single scalp solution lets a prescriber apply both in one daily step rather than layering separate products. The prescriber determines whether the combination, the strengths, and the topical route are appropriate for each patient.
🧪 Supported by a Beyond-Use-Date Stability Study
Formulation quality you can stand behind.
📊 Studied stability
TrichoSol™ is supported by a beyond-use-date study, so the assigned BUD reflects tested stability rather than a default estimate.
🔁 Practical dispensing
A studied BUD can support a supply duration that fits a treatment course and reduces frequent refills.
🏭 Purpose-built lab
Prepared in our USP <795> non-sterile compounding lab in Chino, CA.
❓ What is a beyond-use date (BUD)?
A beyond-use date is the date after which a compounded preparation should not be used. When a formulation is supported by a stability study — as TrichoSol™ is — the BUD reflects laboratory-tested stability data rather than a conservative default, which can support a more practical dispensing quantity while maintaining formulation quality.
⭐ For Your Practice & Your Patients
🩺 For Prescribers
- Two mechanisms in one prescriber-directed solution
- A studied, stability-supported beyond-use date
- Compounded to your specified parameters
- Direct pharmacist access for formulation questions
💇 For Patients
- One daily topical step instead of separate products
- Applied directly to the scalp
- Prepared by a licensed compounding pharmacy team
- Used as directed by the prescriber
📚 The Evidence Base
Oral finasteride and topical minoxidil are FDA-approved treatments for androgenetic alopecia; topical finasteride is studied as an alternative route intended to focus delivery at the scalp. A 2025 systematic review and meta-analysis of seven randomized controlled trials reported that topical minoxidil-finasteride combination therapy showed greater improvement in hair density and diameter than minoxidil monotherapy for male AGA, while noting heterogeneity and small sample sizes and calling for larger confirmatory trials. Individual trials have varied — a separate 2025 randomized controlled trial found improvement from baseline in both groups but no statistically significant difference between the combination and minoxidil alone.
Mixwell compounds to your prescription. The prescriber determines whether TrichoSol™, the strengths, and the topical route are appropriate for each patient based on individual evaluation.
⚠️ Important safety information — finasteride
Pregnancy exposure risk: Finasteride can affect the development of a male fetus. Women who are pregnant or may become pregnant should not handle this preparation, and prescribers should counsel patients on avoiding exposure to partners who are pregnant or may become pregnant, per finasteride labeling.
Systemic considerations: Finasteride — including topical use — can be systemically absorbed. Reported effects associated with finasteride include sexual and mood-related adverse effects. Prescribers assess suitability and counsel patients accordingly.
This information is not exhaustive. The prescriber is responsible for patient selection, counseling, and monitoring.
🚀 How to Send a Prescription
- Specify TrichoSol™ (or minoxidil/finasteride strengths), form, quantity, and Sig on your prescription.
- Fax or e-prescribe to Mixwell Compounding Pharmacy in Chino, CA.
- Call (909) 378-7301 to confirm the formulation and current turnaround time.
- Your patient picks up at our Chino pharmacy, or we can deliver — we serve patients across California.
❓ Frequently Asked Questions
What is TrichoSol™?
TrichoSol™ is the base for Mixwell's compounded Minoxidil 7.5% / Finasteride 0.1% topical scalp solution, prepared pursuant to a prescription and supported by a beyond-use-date stability study. It combines two mechanisms in one daily application for androgenetic alopecia.
Is topical finasteride FDA-approved?
Oral finasteride and topical minoxidil (2% and 5%) are FDA-approved for androgenetic alopecia. Compounded topical finasteride and this combination solution are not FDA-approved; they are prepared individually pursuant to a valid prescription.
Who should not handle this preparation?
Women who are pregnant or may become pregnant should not handle finasteride-containing preparations, because finasteride can affect the development of a male fetus. Prescribers counsel patients on safe handling and exposure precautions per finasteride labeling.
Does the BUD study matter?
Yes. Because TrichoSol™ is supported by a beyond-use-date stability study, its assigned BUD reflects tested stability data rather than a conservative default — which can support a practical dispensing quantity while maintaining formulation quality.
Does Mixwell accept insurance?
Mixwell does not accept insurance. Call (909) 378-7301 for current pricing.
Partner With Mixwell for Custom Hair-Loss Formulations
Mixwell Compounding Pharmacy
13788 Roswell Ave, Ste 158 · Chino, CA 91710
PCCA Member · CA Licensed · USP <800> · Non-Sterile Compounding · Delivery Across California
📞 Call (909) 378-7301References: Zhang Y, Zhou Z, et al. Comparing minoxidil-finasteride mixed solution with minoxidil solution alone for male androgenetic alopecia: a systematic review and meta-analysis of randomized controlled trials. Front Med. 2025. | Lubis FF, Legiawati L, Saulina M, Saldi SRF. Randomized controlled trial on the efficacy and safety of the combination therapy of topical 0.1% finasteride – 5% minoxidil in male androgenetic alopecia. Arch Dermatol Res. 2025;317(1):691. (NCT05990400) | Finasteride prescribing information (pregnancy and handling precautions), U.S. FDA labeling. | Minoxidil and finasteride are compounded pursuant to prescription; TrichoSol™ is supported by a beyond-use-date stability study. | Educational information for licensed prescribers; not a substitute for clinical judgment. Reviewed by Mixwell Compounding Pharmacy compounding team, Chino, CA.