Enrofloxacin Compounded Capsules for Dogs and Cats

Why it is compounded

The approved pet product is a chewable tablet in three strengths [1]. A veterinarian who needs a dose between those strengths, or a form a pet will accept, may order a capsule compounded.

Dosage forms and strengths

• mg per capsule set by the veterinarian
• Filler chosen with the pharmacist, dye free on request
• Quantities matched to the prescription

Dosing is the veterinarian's decision.

How Mixwell prepares it

Mixwell compounds these capsules in Chino, California under USP 795 rules for non sterile preparations [3]. The FDA says compounding animal drugs from bulk drug substances is not allowed [2], so our pharmacist confirms the source of the enrofloxacin before compounding. We also confirm the strength with the veterinarian and set the beyond use date. We ship across California. Veterinary prescriptions cannot be charged to an HSA or FSA account.

The Baytril label lists these contraindications: known sensitivity to quinolones, and small and medium breed dogs during rapid growth, about 2 to 8 months old. Safety is not established for large and giant breeds while growing [1].

In cats, the label warns of rare retinal toxicity and says not to exceed 5 mg/kg per day. It advises caution in animals with known or suspected CNS disorders, since seizures have been rarely reported, and says quinolones are linked to cartilage damage in young animals [1].

Reported reactions include vomiting, diarrhea, loss of appetite, lethargy, ataxia, and seizures. In cats, reports also include dilated pupils, retinal degeneration, and vision loss [1]. The label is for animal use only. People with quinolone hypersensitivity should avoid contact, and eye exposure should be flushed with water [1].

These warnings come from the tablet label. No FDA labeling describes a capsule made by a pharmacy. Diagnosis, dosing, and monitoring are the veterinarian's responsibility.